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Additional benefits of Amitriptyline:  Amitriptyline, which is widely used in the management of chronic neuropathic (nerve) pain, has been found to have additional benefits in terms of possible improvement of memory problems associated with pain.

It is well recognised that patients with chronic and persistent pain often report anxiety and depression. However, pain may also be associated with impairment of memory and mental function.  

In a study, published this month in the European Journal of Anaesthesiology, investigators have confirmed that persistent nerve pain has adverse effects on learning and memory and have shown that the medication amitriptyline can reduce memory impairment by upregulation of chemicals in the brain.

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